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The acting director of the Hospital Authority, Ko Wing-man, said were increasing the dosage and applying the treatment earlier to try to cure people before they have to receive intensive care. But he warned of potentially severe side-effects including heart, blood and kidney problems. Despite efforts to find an effective treatment for the disease, an expert expressed concern that the virus has mutated after he observed that patients at the Prince of Wales Hospital, which was hard-hit by a SARS outbreak, displayed differences in infectiousness, symptoms and the severity of their illness. Preliminary investigations revealed that the coronavirus, believed to be causing SARS, has ``mutated, but not to a great extent,'' said the biochemist, Stephen Tsui of the Chinese University of Hong Kong on Monday. AP
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